History of Batten Disease

Batten disease, a common name for a rare class of diseases called neuronal ceroid lipofuscinoses (NCLs), was first described in 1903 by British neurologist and pediatrician Frederick Batten.

Today, there are 13 known subtypes of Batten disease. Symptoms and disease management for each subtype of Batten disease vary, although several subtypes share similar features and symptoms. Batten disease originally referred specifically to the juvenile-onset type of NCL, but now has been used more generally to describe all types of NCLs. Batten disease affects an estimated 2-4 out of every 100,000 children in the United States.

History of CLN5 (Neuronal Ceroid Lipofuscinosis 5)
Neuronal Ceroid Lipofuscinosis 5, CLN5, was first reported in 1991. It is an inherited neurological disease that affects both motor and sensory nerves. To date, more than 85 known cases of CLN5 exist in scientific literature.

CLN5 affects children globally, across ethnicities and races, and was first diagnosed in the Finnish population.

Living Batten | Batten History: CLN5

CLN4 and CLN9 genes have still not been identified.

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