Signs and symptoms start to become most noticeable during this stage. The signs that are most commonly seen during this time may include:

• Continued learning disabilities, including struggles with concentration and memory issues
• Vision problems or impairments
• Recurrent seizures, or epilepsy
• Uncontrollable muscle jerks (myoclonusBrief, shock-like jerks or twitching of a muscle (myoclonus).)
• Motor clumsiness
• Difficulty coordinating movements