As the disease continues to progress through adolescent years, other symptoms may become apparent:

• Vision deterioration
• Progressive dementiaThe loss of cognitive functioning which includes thinking, remembering, and reasoning which result in behavioral issues that interfere with an individual’s daily life.
• Decline in language ability
• Difficulty eating
• Loss of motor function

Challenges with cognitive and motor skills may be perceived as behavioral issues such as hyperactivityA condition of being overly active., anxiety, and obsessive activities. The child’s description of vision loss associated with CLN5 may be interpreted as hallucinations by parents or caregivers.