Children with CLN7 typically experience normal development until about the age of 2 years. Initial common signs and symptoms may include:

• Vision deterioration
• Recurrent seizures, or epilepsy
• Twitching movements (myoclonusBrief, shock-like jerks or twitching of a muscle (myoclonus).)
• Difficulty sleeping
• Motor clumsiness
• Loss of motor skills that were previously acquired (developmental regressionWhen a child loses an acquired function, milestone or fails to progress beyond a prolonged plateau after a period of relatively normal development.)