Children with CLN7 typically experience normal development until about the age of 2 years. Initial common signs and symptoms may include:
- Vision deterioration
- Recurrent seizures, or epilepsy
- Twitching movements (myoclonusBrief, shock-like jerks or twitching of a muscle (myoclonus).)
- Difficulty sleeping
- Motor clumsiness
- Loss of motor skills that were previously acquired (developmental regressionWhen a child loses an acquired function, milestone or fails to progress beyond a prolonged plateau after a period of relatively normal development.)