The purpose of a There are two types of natural history studies: prospective and retrospective. A natural history study examines a group of people who have a specific medical condition or disease or are at risk of developing one. A natural history is non-interventional and collects health information in order to understand how the medical condition or disease develops and how to possibly treat it. No treatment or investigational product is given. In a prospective study, this data collection is forward-looking and is done over time in the future. In a retrospective study, researchers review and examine factors related to an outcome in the past by looking back on past exposures and medical events. of Late Infantile Variant CLN5 and CLN7 Disease is to better understand two rare forms of Batten disease. It aims to:
- Understand and document the medical history, clinical characteristics, progression of symptoms, and medical events in individuals with CLN5 and CLN7.
- Provide greater understanding of clinically meaningful outcome measures to help inform endpoint selection for future clinical trials.