Once a working version of the gene has been injected into the body or deposited through an IV, there are a few different ways to deliver a vector biologically.
- In the first technique, the working gene is inserted into a harmless virus that has been stripped of its own genes. This virus can enter the cell containing the mutated gene to deliver the working gene.
- In another scenario, the cells containing the faulty genes are taken from the body and the new version of the gene is either injected or “spliced” into the cells. The cells are held in a laboratory to grow before being replaced into the body.
- The use of stem cells is another technique being explored. In this instance, stem cells are manipulated to accept new genes that are malleable to change depending on the course of treatment.