Discover helpful resources and support for CLN5 Batten disease, a rare neurological disease

Batten disease is a group of rare, inherited diseases of the nervous system also called neuronal ceroid (SEHR-oyd) lipofuscinoses (LIE-poh-fuss-kin-OH-seez), or NCLs. Each NCL disease is determined by the gene that causes it. The name of each gene begins with CLN — ceroid lipofuscinosis, neuronal — followed by a unique number that indicates the subtype of Batten disease. The different subtypes have many common features, but differ in terms of age of onset and rate of progression. Signs and symptoms most commonly develop in childhood. Earlier onset disease tends to progress more rapidly.

CLN5 is a late infantile (meaning pediatric-onset) and rapidly progressive subtype of Batten disease. Children with CLN5 typically develop signs and symptoms of their disease at a young age, including seizures, progressive deterioration in intellectual and motor capabilities, loss of vision, and a shortened lifespan.

See below to learn more about Batten disease, read about a family affected by CLN5 Batten disease, and learn how your child with CLN5 may be eligible to enroll in a CLN5 gene therapy clinical trial or a CLN5 Batten disease natural history study.

^{Source: Batten Disease Fact Sheet. (2019, June 24). Retrieved August 8, 2019, from link.}